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Filtered Search Results
Medchemexpress LLC Grazoprevir potassium salt | 1206524-86-8 | C38H49KN6O9S | 1 ML
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Grazoprevir potassium salt is a selective inhibitor of Hepatitis C virus NS3/4a protease with broad activity across various genotypes and resistant variants. It also inhibits SARS-CoV-2 3CLpro activity. This product is for research use only.
- Selective inhibitor of Hepatitis C virus NS3/4a protease
- Broad activity across various genotypes and resistant variants
- Inhibits SARS-CoV-2 3CLpro activity
- Potent against HCV replication mutants NS5A (Y93H), NS5B nucleosides (S282T), and NS5B (C316Y)
- Demonstrates in vivo efficacy against chronic-HCV-infected chimpanzees
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Medchemexpress LLC Pemirolast potassium | 100299-08-9 | 99.99% | 5 MG
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Pemirolast potassium is an orally active antiallergic agent effective in research for bronchial asthma and conjunctivitis. This compound acts as an H1 receptor inhibitor, preventing the activation of human eosinophils to inhibit granule protein release, thereby alleviating allergic diseases. It also attenuates hypersensitivity reactions by inhibiting the release of sensory neuropeptides.
- Orally active antiallergic agent
- Attenuates hypersensitivity reactions
- Useful for bronchial asthma and conjunctivitis research
- Acts as an H1 receptor inhibitor
- Inhibits eosinophil activation and granule protein release
- Suppresses degranulation reactions in mast cells
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Medchemexpress LLC Pemirolast potassium | 100299-08-9 | 99.99% | 50 MG
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Pemirolast potassium is an orally active antiallergic agent that attenuates Paclitaxel hypersensitivity reactions. It can be used for bronchial asthma and conjunctivitis research.
- Orally active antiallergic agent
- Attenuates paclitaxel hypersensitivity reactions
- Used for bronchial asthma and conjunctivitis research
- Inhibits A23187-induced LTC4 and ECP release from eosinophils
- Inhibits PAF-induced and FMLP-induced ECP release from eosinophils
- Reduces cisplatin-induced kaolin intake and inhibits cisplatin-induced substance P release in the cerebrospinal fluid
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Medchemexpress LLC Bromodomain inhibitor-8 | 98.0% | 1 MG
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Bromodomain inhibitor-8 (Intermediate 21) is a BET bromodomain inhibitor used for treating autoimmune and inflammatory diseases.
- Acts as a BET bromodomain inhibitor
- Used for treating autoimmune diseases
- Used for treating inflammatory diseases
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Pickering Laboratories Inc Artificial Perspiration, ISO 105-B07/105-E04, pH 8.0, Stabilized, each (200 mL/bottle)
Perspiration is on everything we touch with our fingers or that comes into contact with our bodies. Sweat can react with materials and trigger allergies, or it can shorten product service life via corrosion or discoloration. Natural human perspiration has a complex composition that depends on the type of sweat gland, the person’s metabolism and hydration level. These test solutions are for all kinds of textiles and textiles in all forms. Textiles are wetted with either the acidic or alkaline solution to test the combined effect of perspiration solution and exposure to light according to ISO 105-B07, and to perspiration only according to ISO 105-E04. The pH of the acidic solution is 5.5 and that of the alkaline solution is 8.0.
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Pickering Laboratories Inc Artificial Sebum, ASTM D4265-14, Not Stabilized, each (500 g/bottle) (Minimum order of 5 bottles)
Sebum is an oily secretion produced by sebaceous glands, which spreads over the hair and skin for waterproofing purposes. Pickering Labs manufactures an artificial sebum formulation according to ASTM D4265-14 or ASTM D4265-98. It is ready-to-use and provides the reliability, reproducibility and convenience needed for testing. This formulation can be used according to AATCC Standard Test Method 130-2010 for evaluating the efficacy of home laundry products and conditions to remove stains from fabric
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Medchemexpress LLC Mutant IDH1 inhibitor | 1429180-08-4 | 99.1% | 466.58 | 10 MM 1 ML
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Mutant IDH1 inhibitor is a potent mutant IDH1 R132H inhibitor with an IC50 of < 72 nM. It is used for the treatment of diseases or disorders associated with such mutant IDH proteins, including cell-proliferation disorders, such as cancer.
- Potent mutant IDH1 R132H inhibitor
- IC50 of < 72 nM
- Treats diseases associated with mutant IDH proteins
- Applicable for cell-proliferation disorders including cancer
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Medchemexpress LLC Deschloroetizolam | 40054-73-7 | 99.8% | 308.41 | 50 MG
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Deschloroetizolam is a designer Benzodiazepine, identified as a psychoactive substance with various physical and cognitive effects.
- Designer benzodiazepine
- Psychoactive substance
- Physical and cognitive effects
- For research use only
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Medchemexpress LLC Deschloroetizolam | 40054-73-7 | 99.8% | 308.41 | 100 MG
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Deschloroetizolam is a designer Benzodiazepine, a psychoactive substance with physical and cognitive effects. It is intended for research use only, not for sale to patients. This solid, white to off-white compound has a molecular weight of 308.41. It exhibits high solubility in DMSO, reaching 125 mg/mL (405.30 mM).
- Intended for research use only
- Psychoactive substance with physical and cognitive effects
- Appears as a white to off-white solid
- Highly soluble in DMSO (125 mg/mL)
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Medchemexpress LLC Mutant EGFR inhibitor | 1421373-62-7 | 99.4% | 520.03 | 50 MG
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Mutant EGFR inhibitor (Example 25) is a potent mutant EGFR inhibitor. It inhibits FGFRWT with an IC50 of 0.41 nM. This inhibitor also targets EGFRL858R, EGFRExon 19 deletion, and EGFRT790M. It is intended for the study of diseases mediated by EGFR, especially cancers, and is for research use only, not for sale to patients.
- Potent mutant EGFR inhibitor
- Inhibits FGFRWT with an IC50 of 0.41 nM
- Targets EGFRL858R, EGFRExon 19 deletion, and EGFRT790M
- Used for the study of diseases mediated by EGFR, particularly cancers
- For research use only
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Transene Inc Nickel Etchant TFB | 1 Gallon
Standard nickel etchant for evaporated nickel films.
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Medchemexpress LLC K-Ras(G12C) inhibitor 12 | 1469337-95-8 | 99.6% | 449.67 | 100 MG
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K-Ras(G12C) inhibitor 12 is an irreversible inhibitor of K-Ras(G12C) that can alter the nucleotide-binding preference of K-Ras and block its interaction with effector proteins. It can reduce cell viability and induce apoptosis in lung cancer cell lines with G12C mutations and has anti-tumor activity.
- Irreversible inhibitor of K-Ras(G12C)
- Alters nucleotide-binding preference of K-Ras
- Blocks interaction with effector proteins
- Reduces cell viability and induces apoptosis in lung cancer cell lines with G12C mutations
- Has anti-tumor activity
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LaMarKa Chemical Company Titration Solvent for Neutral Numbers ASTM D 974
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Titration Solvent For Neutral Numbers, Astm-D 974 - Bottle 4L Amber Safety
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![Medchemexpress LLC 1-[4-[6-methyl-5-(3,4,5-trimethoxyphenyl)-3-pyridinyl]phenyl]piperazine | 1627503-67-6 | MFCD28168043 | 99.5% | 419.52 g/mol | C25H29N3O3 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000289256.png-250.jpg)
Medchemexpress LLC 1-[4-[6-methyl-5-(3,4,5-trimethoxyphenyl)-3-pyridinyl]phenyl]piperazine | 1627503-67-6 | MFCD28168043 | 99.5% | 419.52 g/mol | C25H29N3O3 | 10 MG
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LDN-214117 is a selective small-molecule inhibitor of Activin receptor-like kinase 2 (ALK2/ACVR1) used in research to modulate BMP/TGF-β signaling. It is orally active, shows brain penetration, and demonstrates nanomolar potency against ALK2, making it suitable for biochemical and cellular studies and kinase target validation.
- Nanomolar potency against ALK2 (IC50 24 nM).
- High selectivity over related receptors (for example, >100-fold vs ALK5).
- Purity 99.54% by HPLC.
- Available as solid (including 5 mg and 10 mg) and as a 10 mM solution in DMSO.
- Suitable for biochemical and cellular BMP/TGF-β pathway studies.
- Certificate of analysis and safety data sheet available.
- Recommended storage: powder at -20°C; solutions at -80°C.
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Medchemexpress LLC Deschloroetizolam | 40054-73-7 | 99.29% | 308.41 | 1 ML
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Deschloroetizolam is a designer Benzodiazepine and a psychoactive substance with physical and cognitive effects. It is intended for research use only.
- For high-speed applications
- 50 mL capacity
- Leak-resistant cap
- Suitable for laboratory centrifugation
- Suitable for storage
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